Ondansetron

Ondansetron
Clinical data
Trade names	Zofran Ondisolv
AHFS/Drugs.com	Stampa:Drugs.com
MedlinePlus	a601209
Pregnancy; category	AU: B1; ;
Routes of; administration	Oral, rectal, IV, IM
ATC code	A04AA01 (WHO) ;
Legal status
Legal status	AU: S4 (Prescription only) ; CA: ℞-only ; UK: POM (Prescription only) ; US: ℞-only ;
Pharmacokinetic data
Bioavailability	~60%
Protein binding	70%-76%
Metabolism	Hepatic (CYP3A4, CYP1A2, CYP2D6)
Elimination half-life	5.7 hours
Excretion	Renal
Identifiers
	IUPAC name (RS)-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-2,3-dihydro-1H-carbazol-4(9H)-one;
CAS Number	99614-02-5[CAS];
PubChem CID	4595;
IUPHAR/BPS	2290;
DrugBank	DB00904Stampa:Drugbankcite;
ChemSpider	4434 ;
UNII	4AF302ESOS;
KEGG	D00456 ;
ChEMBL	ChEMBL46 ;
CompTox Dashboard (EPA)	DTXSID8023393 ;
ECHA InfoCard	100.110.918
Chemical and physical data
Formula	C18H19N3O
Molar mass	293.4 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C3c2c1ccccc1n(c2CCC3Cn4ccnc4C)C;
	InChI InChI=1S/C18H19N3O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2/h3-6,9-10,13H,7-8,11H2,1-2H3Stampa:Stdinchicite; Key:FELGMEQIXOGIFQ-UHFFFAOYSA-NStampa:Stdinchicite;
	(verify)

Ondansetron është emri i një ilaçi që përdoret kryesisht si antiemetik (për trajtimin e të vjellave). Ilaçi vepron në sistemin nervor qëndror dhe periferik, duke shërbyer si anatagonist i receptorëve 5-HT3 të serotoninës.