tivozanib

instancë e

type of chemical entity

nënklasë e

përbërje kimike

përdor

Barnat

strukturë kimike

masa

454,104 dalton^[3]

formula kimike

C₂₂H₁₉ClN₄O₅^[3]

kanonikja SMILES

CC1=CC(=NO1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)Cl^[3]

isomeric SMILES

CC1=C/C(=N\C(=O)Nc2ccc(cc2Cl)Oc3ccnc4c3cc(c(c4)OC)OC)/NO1^[14]

reagon fizikisht me

Fms related receptor tyrosine kinase 1^[15]

subjekti ka rol: enzyme inhibitor

Fms related receptor tyrosine kinase 4^[15]

subjekti ka rol: enzyme inhibitor

Kinase insert domain receptor^[15]

subjekti ka rol: enzyme inhibitor

Reference

1. ^ ^{a b} Global Substance Registration System, 18 nëntor 2016, anglisht, tivozanib, 172030934T
2. ^ CAS Common Chemistry, 7 prill 2021, https://commonchemistry.cas.org/detail?cas_rn=475108-18-0, SPMVMDHWKHCIDT-UHFFFAOYSA-N
3. ^ ^{a b c d e f} PubChem, 18 nëntor 2016, anglisht, 9911830, Tivozanib
4. ^ ^{a b c d e} SPMVMDHWKHCIDT-UHFFFAOYSA-N, InChIKey
5. ^ ^{a b} UniChem
6. ^ ChEMBL, 18 nëntor 2016, anglisht, TIVOZANIB, CHEMBL1289494
7. ^ ChEBI release 2020-09-01
8. ^ IUPHAR/BPS Guide to PHARMACOLOGY, 18 nëntor 2016, anglisht, 6058, tivozanib
9. ^ ChEBI, 19 tetor 2016, anglisht, 1-[2-chloro-4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-3-(5-methyl-3-isoxazolyl)urea, 91327
10. ^ International Chemical Identifier, InChI=1S/C22H19ClN4O5/c1-12-8-21(27-32-12)26-22(28)25-16-5-4-13(9-15(16)23)31-18-6-7-24-17-11-20(30-3)19(29-2)10-14(17)18/h4-11H,1-3H3,(H2,25,26,27,28)
11. ^ Protein Data Bank, 19 tetor 2016, anglisht, 4ASE, 4ASE
12. ^ ChemSpider, 18 nëntor 2016, anglisht, 8087481, Tivozanib
13. ^ inferred from InChIKey
14. ^ RCSB protein data bank, 16 shkurt 2021, AV9, anglisht
15. ^ ^{a b c} IUPHAR/BPS Guide to PHARMACOLOGY, 17 gusht 2016, 6058, anglisht