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metronidazole

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komponim kimik

External resources

MedlinePlus drug identifier
a689011

route of administration: oral administration

a601159

route of administration: intravenous injection

a682244

route of administration: topical medication

a617051

route of administration: intravaginal administration

numri CAS
ZVG number
MeSH descriptor ID
D008795

referuar si: Metronidazole

Encyclopædia Britannica Online ID
science/metronidazole

referuar si: metronidazole

MeSH concept ID
NSC number
ChEMBL ID
Human Metabolome Database ID
MeSH tree code
ECHA Substance Infocard ID
PDB structure ID
DrugCentral ID
Encyclopedia of China (Third Edition) ID
580496

referuar si: 甲硝唑

Probes And Drugs ID
NDF-RT ID
CA PROP 65 ID
Reaxys registry number
611683[10]
PubChem CID
UniChem compound ID
Quora topic ID
PDB ligand ID
SPLASH
PesticideInfo chemical ID
OpenAlex ID
UNII
KBpedia ID
InChIKey
InChI
ScienceDirect topic ID
kodi ATC
ChEBI ID
6909[3][17]

mapping relation type: përputhje e përpiktë

Guide to Pharmacology Ligand ID
HSDB ID
SureChEMBL ID
WikiProjectMed ID
DSSTox substance ID
KEGG ID
ChemSpider ID
Freebase ID
Microsoft Academic ID
Store medisinske leksikon ID
metronidazol[23]

referuar si: metronidazol

mapping relation type: përputhje e përpiktë

DSSTOX compound identifier
UMLS CUI
electronic Essential Medicines List medicine ID
DrugBank ID
AGROVOC ID
numri CE
WordNet 3.1 Synset ID
03762957-n[24]
UNSPSC Code
MassBank accession ID
RxNorm ID
CAMEO Chemicals ID

instancë e

type of chemical entity

nënklasë e

nitroimidazole

përdor

strukturë kimike

reason for preferred rank: preferred chemical structure representation

kriteri i përdorur: structure representation with labelled terminal carbon atoms

image of molecular model or crystal lattice model

përshkruan: ball-and-stick model

masa

171,064 dalton[26]

formula kimike

C₆H₉N₃O₃[11]

kanonikja SMILES

CC1=NC=C(N1CCO)[N+](=O)[O-][11]

defined daily dose

0,5 grami[27]

route of administration: intravaginal administration

1,5 grami[28]

route of administration: parenteral route of administration

active ingredient in

MetroLotion[29]
Vandazole[30]
Noritate[31]
Nuvessa[32]
Flagyl[33]
Nydamax[34]
MetroGel[35]
MetroCream[36]
Rosadan[37]

World Health Organisation international non-proprietary name

metronidazole[10]

found in taxon

Streptomyces hygroscopicus[38]
Neurolaena oaxacana[39]
Actinomadura[40]

medical condition treated

bacteroides infectious disease[41][42]
abscess[41]
rosacea[41][43]
Clostridioides difficile colitis[41][43]
amebiasis[41]
postoperative complications[41]
bacterial vaginosis[41][43]
giardiasis[41]
peripheral vascular disease[41]
sëmundje bakteriale[43]
diverticulitis[43]
dental abscess[43]
gingivitis[43]
amebiasis[44]

approved by: Food and Drug Administration

koha e fillimit: 18 korrik 1963

sëmundje bakteriale[44]

approved by: Food and Drug Administration

koha e fillimit: 18 korrik 1963

botulism

significant drug interaction

fosphenytoin[45]

side effect: peripheral neuropathy

disulfiram[46]

side effect: peripheral neuropathy

Fenitoina[45]

side effect: peripheral neuropathy

disulfiram[46]

side effect: acute psychogenic paranoid psychosis

fosphenytoin[45]

side effect: long QT syndrome

fosphenytoin[45]

side effect: heart arrhythmia

route of administration

oral administration
rectal administration
intravenous infusion and defusion
intravaginal administration
boxed warning[47]

pregnancy category

Australian pregnancy category B2
US pregnancy category B

prodhues

Pfizer[48]

subjekti ka rol

anti-infective agent[49]
antiprotozoal[49]
radiosensitizer[49]
carcinogen[50]
bactericide[51][52]
essential medicine

‎WHO Aware Classification

access[53]

stylized name

metroNIDAZOLE[54]

lëshuar nga: Institute for Safe Medication Practices

ka veçori: Tall Man lettering

kategoria në Commons

Metronidazole

Reference

  1. ^ a b c d e f Global Substance Registration System, 19 nëntor 2016, anglisht, metronidazole, 140QMO216E
  2. ^ CAS Common Chemistry, 8 prill 2021, https://commonchemistry.cas.org/detail?cas_rn=443-48-1, VAOCPAMSLUNLGC-UHFFFAOYSA-N
  3. ^ a b ChEMBL, 19 nëntor 2016, anglisht, METRONIDAZOLE, CHEMBL137
  4. ^ a b inferred from InChIKey
  5. ^ a b c d e f VAOCPAMSLUNLGC-UHFFFAOYSA-N, InChIKey
  6. ^ ECHA Substance Infocard database, 27 dhjetor 2018, 100.006.489, Metronidazole, CAS no.: 443-48-1
  7. ^ Protein Data Bank, 19 tetor 2016, anglisht, 1W3R, 1W3R
  8. ^ a b UniChem
  9. ^ California Proposition 65 list of chemicals, 6 janar 2020, https://oehha.ca.gov/chemicals/metronidazole
  10. ^ a b c ChEBI, 19 tetor 2016, anglisht, metronidazole, 6909
  11. ^ a b c d e PubChem, 19 nëntor 2016, anglisht, 4173, metronidazole
  12. ^ Quora
  13. ^ OpenAlex, 26 janar 2022, https://docs.openalex.org/download-snapshot/snapshot-data-format
  14. ^ KBpedia, 9 korrik 2020
  15. ^ ChEBI release 2020-09-01
  16. ^ a b c d e DrugBank, anglisht, 17 nëntor 2015, DB00916, Metronidazole
  17. ^ InChI=1S/C6H9N3O3/c1-5-7-4-6(9(11)12)8(5)2-3-10/h4,10H,2-3H2,1H3, International Chemical Identifier
  18. ^ IUPHAR/BPS Guide to PHARMACOLOGY, 5 shkurt 2021
  19. ^ Hazardous Substances Data Bank, 10 maj 2021, 28 tetor 2019, METRONIDAZOLE, 3129
  20. ^ Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard
  21. ^ ChemSpider, 19 nëntor 2016, anglisht, 4029, Metronidazole
  22. ^ Freebase Data Dumps, 28 tetor 2013
  23. ^ Great Norwegian Encyclopedia, 30 maj 2020
  24. ^ GF WordNet
  25. ^ DrugBank, anglisht, 17 nëntor 2015, Metronidazole, DB00916
  26. ^ PubChem, 19 tetor 2016, anglisht, 4173, metronidazole
  27. ^ https://www.whocc.no/atc_ddd_index/?code=G01AF01
  28. ^ https://www.whocc.no/atc_ddd_index/?code=J01XD01
  29. ^ RxNorm, 218345, 14 shkurt 2018
  30. ^ RxNorm, 606381, 14 shkurt 2018
  31. ^ RxNorm, 218778, 14 shkurt 2018
  32. ^ RxNorm, 1604332, 14 shkurt 2018
  33. ^ RxNorm, 202866, 14 shkurt 2018
  34. ^ RxNorm, 701916, 14 shkurt 2018
  35. ^ RxNorm, 202869, 14 shkurt 2018
  36. ^ RxNorm, 218343, 14 shkurt 2018
  37. ^ RxNorm, 1148395, 14 shkurt 2018
  38. ^ Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain
  39. ^ Sesquiterpene lactones from neurolaena oaxacana
  40. ^ Polyhalogenation of Isoflavonoids by the Termite-Associated Actinomadura sp. RB99
  41. ^ a b c d e f g h i N0000146194, 13 dhjetor 2016, anglisht, NDF-RT
  42. ^ https://www.ncbi.nlm.nih.gov/pubmed/7457495
  43. ^ a b c d e f g h i Drug Indications Extracted from FAERS, 2 tetor 2018
  44. ^ a b Inxight: Drugs Database, 2 nëntor 2018, https://drugs.ncats.io/drug/140QMO216E, http://www.accessdata.fda.gov/drugsatfda_docs/label/2015/012623s066lbl.pdf
  45. ^ a b c d A reference set of clinically relevant adverse drug-drug interactions, hypothetically
  46. ^ a b A reference set of clinically relevant adverse drug-drug interactions, probably
  47. ^ FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links., https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802
  48. ^ https://www.pfizer.com/products/product-list
  49. ^ a b c Medical Subject Headings, 15 mars 2018, D008795
  50. ^ California Proposition 65 list of chemicals, 18 mars 2020, https://oehha.ca.gov/chemicals/metronidazole
  51. ^ 6909
  52. ^ ChEBI
  53. ^ 2023 ‎AWaRe classification‎
  54. ^ 2 shtator 2022, https://www.ismp.org/recommendations/tall-man-letters-list