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valproic acid

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komponim kimik

External resources

MedlinePlus drug identifier
LEM ID
MeSH descriptor ID
D014635

referuar si: Valproic Acid

MeSH concept ID
NSC number
ChEMBL ID
Guide to Pharmacology Ligand ID
MeSH tree code
AICS Chemical ID (BEING DELETED)
ECHA Substance Infocard ID
PDB structure ID
DrugCentral ID
CAMEO Chemicals ID
NALT ID
Probes And Drugs ID
LIPID MAPS ID
NDF-RT ID
Freebase ID
CA PROP 65 ID
Reaxys registry number
1750447[10]
Library of Congress ID
sh85141922[11]

referuar si: Valproic acid

PubChem CID
UniChem compound ID
Quora topic ID
YSO ID
22961[15]

referuar si: valproaatti, valproat, valproic acid

PDB ligand ID
SPLASH
KEGG ID
OpenAlex ID
UNII
InChIKey
numri CAS
DrugBank ID
ChEBI ID
39867[1][20]

mapping relation type: përputhje e përpiktë

WikiProjectMed ID
CosIng number
kodi ATC
Human Metabolome Database ID
SureChEMBL ID
electronic Essential Medicines List medicine ID
DSSTox substance ID
Microsoft Academic ID
numri CE
202-777-3[6]
DSSTOX compound identifier
NMRShiftDB structure ID
UMLS CUI
InChI
ChemSpider ID
BNCF Thesaurus ID
identifikues i BNF
122625973[11]

referuar si: Valproïque, Acide

National Library of Israel J9U ID
World Health Organisation international non-proprietary name numeric ID
MassBank accession ID
RxNorm ID
HSDB ID

instancë e

type of chemical entity

nënklasë e

branched chain fatty acids

fillimi

1967[30]

strukturë kimike

masa

144,115 dalton[31]

ngjarje e rëndësishme

Dépakine case

conjugate base

valproate

formula kimike

C₈H₁₆O₂[12]

kanonikja SMILES

CCCC(CCC)C(=O)O[12]

World Health Organisation international non-proprietary name

valproic acid[16][32]

found in taxon

Valeriana officinalis[33]

medical condition treated

early-onset Alzheimer's disease[34]
childhood absence epilepsy[34]
complex partial seizure[34]

reagon fizikisht me

histone deacetylase 1[35]

subjekti ka rol: enzyme inhibitor

Aldehyde dehydrogenase 5 family member A1[36]

subjekti ka rol: reaction inhibitor

legal status (medicine)

boxed warning[37]

pregnancy category

Australian pregnancy category D
US pregnancy category X

subjekti ka rol

enzyme inhibitor[38]
anticonvulsant agent[38]
GABA agents[38]
antimanic agents[38]
essential medicine
developmental toxicant[39]

koha e fillimit: 1 korrik 1987

formë tjetër

valproate
sodium valproate
valproate calcium

kategoria në Commons

Valproic acid

Reference

  1. ^ a b ChEMBL, 19 nëntor 2016, anglisht, VALPROIC ACID, CHEMBL109
  2. ^ IUPHAR/BPS Guide to PHARMACOLOGY, 19 nëntor 2016, anglisht, 7009, valproic acid
  3. ^ ECHA Substance Infocard database, 27 dhjetor 2018, 100.002.525, 2-propylvaleric acid, CAS no.: 99-66-1
  4. ^ Protein Data Bank, 19 tetor 2016, anglisht, 1DIT, 1DIT
  5. ^ a b UniChem
  6. ^ a b c d e f Global Substance Registration System, 19 nëntor 2016, anglisht, valproic acid, 614OI1Z5WI
  7. ^ N0000020512, 26 shkurt 2018, NDF-RT
  8. ^ Freebase Data Dumps, 28 tetor 2013
  9. ^ California Proposition 65 list of chemicals, 7 janar 2020, https://oehha.ca.gov/chemicals/valproate
  10. ^ ChEBI, 19 tetor 2016, anglisht, valproic acid, 39867
  11. ^ a b Nuovo soggettario, https://thes.bncf.firenze.sbn.it/termine.php?id=52464, 17 qershor 2021
  12. ^ a b c d e PubChem, 19 nëntor 2016, anglisht, 3121, VALPROIC ACID
  13. ^ a b c d e f g NIJJYAXOARWZEE-UHFFFAOYSA-N, InChIKey
  14. ^ Quora
  15. ^ YSO-Wikidata mapping project, 9 shkurt 2022
  16. ^ a b ChEMBL, 19 janar 2016, anglisht, Valproic Acid, CHEMBL109
  17. ^ a b OpenAlex, 26 janar 2022, https://docs.openalex.org/download-snapshot/snapshot-data-format
  18. ^ ChEBI release 2020-09-01
  19. ^ CAS Common Chemistry, 9 prill 2021, NIJJYAXOARWZEE-UHFFFAOYSA-N, https://commonchemistry.cas.org/detail?cas_rn=99-66-1
  20. ^ International Chemical Identifier, InChI=1S/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10)
  21. ^ CosIng database, 28 dhjetor 2019, 94126, VALPROIC ACID, CAS no.: 99-66-1
  22. ^ DrugBank, anglisht, 17 nëntor 2015, 00313, Valproic Acid
  23. ^ a b inferred from InChIKey
  24. ^ Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard
  25. ^ ChemSpider, 19 nëntor 2016, anglisht, 3009, Valproic acid
  26. ^ National Central Library of Florence
  27. ^ Biblioteka Kombëtare e Izraelit
  28. ^ https://mednet-communities.net/inn/db/ViewINN.aspx?i=3300
  29. ^ Hazardous Substances Data Bank, 10 maj 2021, 28 tetor 2019, VALPROIC ACID, 3582
  30. ^ https://www.aljazeera.com/economy/2020/8/3/frances-sanofi-charged-with-manslaughter-in-birth-defects-case
  31. ^ PubChem, 19 tetor 2016, anglisht, 3121, VALPROIC ACID
  32. ^ Recommended INN: List 13, 1973
  33. ^ Alkaloid-Bearing Plants and Their Contained Alkaloids. 1957-1968
  34. ^ a b c d N0000147028, 13 dhjetor 2016, NDF-RT, anglisht
  35. ^ IUPHAR/BPS Guide to PHARMACOLOGY, 17 gusht 2016, 7009, anglisht
  36. ^ Open Targets Platform, 14 gusht 2023, https://platform.opentargets.org/drug/CHEMBL109
  37. ^ FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links., https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802
  38. ^ a b c d Medical Subject Headings, 15 mars 2018, D014635
  39. ^ California Proposition 65 list of chemicals, 19 mars 2020, https://oehha.ca.gov/chemicals/valproate