fentanyl
Appearance
komponim kimik
instancë e
type of chemical entity
nënklasë e
phenethylamine
piperidine
N,N-disubstituted primary carboxamide
përdor
strukturë kimike
image of molecular model or crystal lattice model
përshkruan: ball-and-stick model
përshkruan: space-filling model
masa
336,220164 dalton[23]
associated hazard
fentanyl toxicity
shkak i
fentanyl toxicity
zbulues
Paul Janssen
data: 1960
formula kimike
C₂₂H₂₈N₂O[10]
kanonikja SMILES
CCC(=O)N(C1CCN(CC1)CCC2=CC=CC=C2)C3=CC=CC=C3[10]
melting point
83±1 Celcius[24]
safety classification and labelling
NFPA 704: Standard System for the Identification of the Hazards of Materials for Emergency Response[25]
NFPA Special: s’ka vlerë
NFPA Health: 4
NFPA Fire: 1
NFPA Instability: 0
median lethal dose (LD50)
3,1 milligram per kilogram
route of administration: vlerë e panjohur
applies to taxon: laboratory rat
active ingredient in
Effentora[26]
Pecfent[27]
Fentora[28]
Abstral[29]
Ionsys[30]
Duragesic[31]
Lazanda[32]
Actiq[33]
Subsys[34]
World Health Organisation international non-proprietary name
fentanyl[9]
medical condition treated
osteoarthritis susceptibility 1[36]
complex regional pain syndrome[36]
peripheral neuropathy[36]
significant drug interaction
isocarboxazid[37]
phenelzine[37]
procarbazine[37]
(±)-deprenyl[37]
amiodarone[38]
reagon fizikisht me
legal status (medicine)
boxed warning[41]
pregnancy category
Australian pregnancy category C
US pregnancy category C
LiverTox likelihood score
LiverTox toxicity likelihood category E[42]
përshkruar nga burimi
Opium Law
subjekti ka rol
opioid receptor agonist[43]
opioid[44]
narcotic[44]
anesthesia adjuvants[44]
intravenous anesthetics[44]
controlled substance
essential medicine
stylized name
MCN code
2933.33.63
kategoria në Commons
Fentanyl
kategoria kryesore
Category:Fentanyl
Reference
- ^ a b ChEMBL, 19 nëntor 2016, anglisht, FENTANYL, CHEMBL596
- ^ BBC Things
- ^ a b inferred from InChIKey
- ^ a b c d e f PJMPHNIQZUBGLI-UHFFFAOYSA-N, InChIKey
- ^ ECHA Substance Infocard database, 27 dhjetor 2018, 100.006.468, Fentanyl, CAS no.: 437-38-7
- ^ a b UniChem
- ^ a b c d e Global Substance Registration System, 19 nëntor 2016, anglisht, fentanyl, UF599785JZ
- ^ Freebase Data Dumps, 28 tetor 2013
- ^ a b c ChEBI, 3 tetor 2016, anglisht, fentanyl, 119915
- ^ a b c d e PubChem, 19 nëntor 2016, anglisht, 3345, fentanyl
- ^ YSO-Wikidata mapping project
- ^ a b DrugBank, anglisht, 17 nëntor 2015, 00813, Fentanyl
- ^ OpenAlex, 26 janar 2022, https://docs.openalex.org/download-snapshot/snapshot-data-format
- ^ ChEBI release 2020-09-01
- ^ InChI=1S/C22H28N2O/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19/h3-12,21H,2,13-18H2,1H3, International Chemical Identifier
- ^ Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard
- ^ KBpedia, 9 korrik 2020
- ^ Immune Epitope Database and Analysis Resource, 1 mars 2022, 153507
- ^ CAS Common Chemistry, 6 prill 2021, PJMPHNIQZUBGLI-UHFFFAOYSA-N, https://commonchemistry.cas.org/detail?cas_rn=437-38-7
- ^ ChemSpider, 19 nëntor 2016, anglisht, 3228, Fentanyl
- ^ IUPHAR/BPS Guide to PHARMACOLOGY, 19 nëntor 2016, anglisht, 1626, fentanyl
- ^ Hazardous Substances Data Bank, 10 maj 2021, 28 tetor 2019, Fentanyl, 3329
- ^ PubChem, 3 tetor 2016, anglisht, 3345, fentanyl
- ^ http://www.cdc.gov/niosh/ershdb/emergencyresponsecard_29750022.html
- ^ 5 maj 2018, https://www.cdc.gov/niosh/ershdb/emergencyresponsecard_29750022.html
- ^ http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/000833/human_med_000754.jsp, 22 mars 2017, EMEA/H/C/000833
- ^ http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/001164/human_med_001387.jsp, 22 mars 2017, EMEA/H/C/001164
- ^ RxNorm, 668619, 14 shkurt 2018
- ^ RxNorm, 1053648, 14 shkurt 2018
- ^ RxNorm, 1666832, 14 shkurt 2018
- ^ RxNorm, 151678, 14 shkurt 2018
- ^ RxNorm, 1115547, 14 shkurt 2018
- ^ RxNorm, 215008, 14 shkurt 2018
- ^ RxNorm, 1237051, 14 shkurt 2018
- ^ N0000147049, 13 dhjetor 2016, anglisht, NDF-RT
- ^ a b c d e f Drug Indications Extracted from FAERS, 2 tetor 2018
- ^ a b c d High-priority drug–drug interactions for use in electronic health records
- ^ 10.3389/FPHAR.2018.01145
- ^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac ad ae af ag ah ai aj ak al am an ao ap aq ar as at au av aw ax ay az ba bb bc bd be bf bg bh bi bj bk bl bm bn bo bp bq br bs bt bu bv bw bx by bz ca cb cc cd A reference set of clinically relevant adverse drug-drug interactions, hypothetically
- ^ a b c IUPHAR/BPS Guide to PHARMACOLOGY, 17 gusht 2016, 1626, anglisht
- ^ FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links., https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802
- ^ LiverTox, 8 prill 2021, https://www.ncbi.nlm.nih.gov/books/n/livertox/FentanylAndAnalogues, 25 prill 2019
- ^ N0000147049, 5 mars 2018, NDF-RT
- ^ a b c d Medical Subject Headings, 15 mars 2018, D005283
- ^ 2 shtator 2022, https://www.ismp.org/recommendations/tall-man-letters-list