azithromycin
komponim kimik
instancë e
type of chemical entity
strukturë kimike
image of molecular model or crystal lattice model
përshkruan: ball-and-stick model
masa
748,509 dalton[15]
formula kimike
C₃₈H₇₂N₂O₁₂[15]
kanonikja SMILES
CCC1C(C(C(N(CC(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)C)O)(C)O[15]
isomeric SMILES
CC[C@@H]1[C@@]([C@@H]([C@H](N(C[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)C)O)(C)O[15]
medical condition treated
bacterial pneumonia[35]
urethritis[35]
upper respiratory tract infection[35]
otitis media[35]
skin infection[35]
staphylococcal infection[35]
lung disease[36]
sëmundje bakteriale[36]
nasopharyngitis[36]
otitis[36]
Mycobacterium avium-intracellulare infection[36]
susceptibility to severe influenza[36]
blepharitis[36]
bronchiolitis obliterans[36]
significant drug interaction
chloroquine[38]
clarithromycin[38]
amiodarone[38]
anagrelide[38]
arsenic trioxide[38]
astemizole[38]
bepridil[38]
cisapride[38]
(RS)-citalopram[38]
disopyramide[38]
dofetilide[38]
domperidone[38]
dronedarone[38]
droperidol[38]
erythromycin[38]
escitalopram[38]
flecainide[38]
halofantrine[38]
haloperidol[38]
ibutilide[38]
mesoridazine[38]
(RS)-methadone[38]
moxifloxacin[38]
pentamidine[38]
pimozide[38]
probucol[38]
procainamide[38]
quinidine[38]
sevoflurane[38]
sotalol[38]
sparfloxacin[38]
(RS)-sulpiride[38]
terfenadine[38]
thioridazine[38]
reagon fizikisht me
legal status (medicine)
boxed warning[41]
pregnancy category
Australian pregnancy category B1
US pregnancy category B
LiverTox likelihood score
LiverTox toxicity likelihood category A[42]
prodhues
Pfizer[43]
WHO Aware Classification
watch[47]
kategoria në Commons
Azithromycin
Reference
- ^ a b c Global Substance Registration System, 18 nëntor 2016, anglisht, azithromycin anhydrous, J2KLZ20U1M
- ^ CAS Common Chemistry, 9 prill 2021, MQTOSJVFKKJCRP-BICOPXKESA-N, https://commonchemistry.cas.org/detail?cas_rn=83905-01-5
- ^ a b ChEMBL, 18 nëntor 2016, anglisht, AZITHROMYCIN, CHEMBL529
- ^ a b inferred from InChIKey
- ^ a b c d e f MQTOSJVFKKJCRP-BICOPXKESA-N, InChIKey
- ^ GF WordNet
- ^ a b ECHA Substance Infocard database, 27 dhjetor 2018, 100.126.551, 2R,3R,4R,5R,8R,10R,11R,13S,14R)-11-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyl-oxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyl-oxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one, CAS no.: 83905-01-5
- ^ Protein Data Bank, 19 tetor 2016, anglisht, 1YHQ, 1YHQ
- ^ Protein Data Bank, 19 tetor 2016, anglisht, 4V7Y, 4V7Y
- ^ Protein Data Bank, 19 tetor 2016, anglisht, 1M1K, 1M1K
- ^ Protein Data Bank, 19 tetor 2016, anglisht, 1NWY, 1NWY
- ^ a b UniChem
- ^ NDF-RT, 19 janar 2016, anglisht, AZITHROMYCIN, N0000148074
- ^ a b c d ChEBI, 19 tetor 2016, anglisht, azithromycin, 2955
- ^ a b c d e f g PubChem, 18 nëntor 2016, anglisht, 447043, azithromycin
- ^ OpenAlex, 26 janar 2022, https://docs.openalex.org/download-snapshot/snapshot-data-format
- ^ KBpedia, 9 korrik 2020
- ^ CAB Thesaurus, 6 prill 2020
- ^ ChEBI release 2020-09-01
- ^ a b DrugBank, anglisht, 17 nëntor 2015, 00207, Azithromycin
- ^ ChEBI release 2019-10-02
- ^ International Chemical Identifier, InChI=1S/C38H72N2O12/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28/h20-33,35,41-43,45-46H,15-19H2,1-14H3/t20-,21-,22+,23-,24-,25+,26+,27-,28+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1
- ^ Freebase Data Dumps, 28 tetor 2013
- ^ 10 shtator 2022, https://golden.com/wiki/Azithromycin-MNNVRN
- ^ Great Norwegian Encyclopedia, 5 qershor 2020
- ^ Medical Subject Headings, 14 mars 2018, D017963
- ^ IUPHAR/BPS Guide to PHARMACOLOGY, 18 nëntor 2016, anglisht, 6510, azithromycin
- ^ Hazardous Substances Data Bank, 10 maj 2021, 28 tetor 2019, AZITHROMYCIN, 7205
- ^ ChemSpider, 18 nëntor 2016, anglisht, 10482163, Azithromycin
- ^ Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard
- ^ N0000148074, 26 shkurt 2018, NDF-RT
- ^ N0000148074, 27 shkurt 2018, NDF-RT
- ^ DrugBank, anglisht, 17 nëntor 2015, Azithromycin, 00207
- ^ https://lingualibre.org/wiki/Q636536
- ^ a b c d e f g h i N0000148074, 13 dhjetor 2016, NDF-RT, anglisht
- ^ a b c d e f g h i j k l m Drug Indications Extracted from FAERS, 2 tetor 2018
- ^ a b c d Inxight: Drugs Database, 2 nëntor 2018, https://drugs.ncats.io/drug/J2KLZ20U1M, http://www.accessdata.fda.gov/drugsatfda_docs/label/2016/050710s043,050711s040,050784s027lbl.pdf
- ^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac ad ae af ag ah ai aj ak High-priority drug–drug interactions for use in electronic health records
- ^ a b A reference set of clinically relevant adverse drug-drug interactions, probably
- ^ IUPHAR/BPS Guide to PHARMACOLOGY, 17 gusht 2016, 6510, anglisht
- ^ FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links., https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802
- ^ LiverTox, 8 prill 2021, https://www.ncbi.nlm.nih.gov/books/n/livertox/Azithromycin, 8 gusht 2017
- ^ https://www.pfizer.com/products/product-list
- ^ N0000148074, 5 mars 2018, NDF-RT
- ^ Medical Subject Headings, 15 mars 2018, D017963
- ^ ChEBI, 2955
- ^ 2023 AWaRe classification